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TABLE OF CONTENTS | REFERENCES | GLOSSARY
Momordica (Momordica charantia)
General Description
Momordica (also known as bitter melon, balsam pear, bitter cucumber, or bitter gourd) is a rapidly growing herbaceous vine native to eastern India and southern China and cultivated widely throughout the world. The plant grows well in a variety of soils, and begins flowering about one month after planting. The warty, cucumber-shaped fruit, which varies in length from 12 to 30 centimeters, is typically harvested while immature, before the seeds harden.

Health Applications

  • Diabetes

History and Traditional Use
Momordica has long been consumed as a vegetable, commonly stuffed, pickled, or sliced into various dishes. The unripe, bitter melon has been used extensively in folk medicine as a remedy for diabetes.1

Chemical Composition
Momordica contains bitter principles (which are responsible for the fruit's characteristic flavor), steroids, and a unique, insulin-like polypeptide known as polypeptide P.1

Momordica and Diabetes
The traditional use of momordica for treatment of diabetes appears to have some merit. Several animal studies indicate that compounds in momordica have hypoglycemic (blood sugar lowering) effects.2-7 In one study conducted on 100 patients with non-insulin dependent diabetes mellitus (NIDDM), hypoglycemic activity was observed in 86 cases.8 Although it is not yet clear just how momordica works to lower blood sugar levels, one study suggests that the hypoglycemic activity results from increased glucose use by the liver rather than an insulin secretion effect.7

Dosage/Toxicity
Dosage recommendations for momordica vary with the form of the herb used. A common recommendation is 2 ounces of fresh juice or equivalent preparations.1 Momordica extracts, which are often standardized to provide consistent levels of bitter principles, usually have dosage recommendations printed on the label. Momordica is commonly consumed as a food and has no known toxicity.


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